Anti-fouling materials based on poly(β-peptoid)s
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United States of America Patent
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Sep 1, 2015
Grant Date -
Nov 29, 2012
app pub date -
May 29, 2012
filing date -
May 26, 2011
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Abstract
Poly(β-peptoid)s selected from the group consisting of poly(N-methyl-β-alanine)s (PMeA) and poly(N-ethyl-β-alanine)s (PEtA) and polyl(methyl-β-alanine-co-ethyl-β-alanine) copolymers (P(MeA-co-EtA) are found to be good anti-fouling materials in that they resist protein adsorption. A process for protecting a surface of an object from protein adsorption comprises the steps of binding such poly(β-peptoid)s to the surface. A medical implant is coated with such poly(β-peptoid)s. A medical drug delivery device is coated with such poly(β-peptoid)s. A filtration device has pores coated with such poly(β-peptoid)s, and an object placed in freshwater or saltwater and having a surface in contact with the freshwater or saltwater has that surface coated with such poly(β-peptoid)s.
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