UV protective skin treatment compositions and screening methods
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United States of America Patent
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Aug 25, 2015
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N/A
app pub date -
Jul 9, 2012
filing date -
Jul 11, 2011
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Abstract
Methods of screening antioxidants for skin protective capacity and antioxidant formulations which protect the skin from UV radiation are disclosed, including using the Briggs-Rauscher Oxidant Method method to one or more antioxidants for predicting protection to the epidermal layer. One antioxidant formulation for use in sunscreens, lip-balms and other types of skincare products for protecting the skin from UV radiation includes a mixture of antioxidants in the skincare product including an effective amount of arbutin in combination with BHT, wherein the ratio of arbutin to BHT ranges from 1:4 to 4:1, and wherein the measured BROM value of the antioxidant mixture is greater than the sum of the BROM values of the individual antioxidants in the mixture at the same concentration. The measured BROM value of the resultant product is greater than or equal to 0.2 sec/μg. The antioxidant formulation may also optionally include hydroquinone, resveratrol, uric acid and/or atorvastatin.
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