Microfluidic devices and methods based on massively parallel picoreactors for cell and molecular diagnostics
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United States of America Patent
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Aug 18, 2015
Grant Date -
Sep 19, 2013
app pub date -
May 4, 2012
filing date -
May 5, 2011
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Abstract
Microfluidic devices and methods of forming cell reactors for performing cell analysis in a microfluidic chip. A microfluidic chip, in one implementation, includes a plurality of trapping sites, each of the plurality of trapping sites having a plurality of micropillars configured to trap one or more cells in an interior space formed by the plurality of micropillars. The plurality of micropillars in each trapping site form a picoreactor for cell and molecular diagnostics, such as characterizing, isolation, processing, and amplification of different cells, cells containing different substances, different particles, different biochemical compositions, proteins, and enzymes.
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