Method for producing 3,4-disubstituted pyrrolidine derivative
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United States of America Patent
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Aug 18, 2015
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Aug 22, 2013
app pub date -
Oct 24, 2011
filing date -
Oct 25, 2010
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Abstract
The present invention provides an inexpensive and industrially advantageous method for producing an optically active form of an anti-(3S,4R)-3-alkylcarbamoyl-4-hydroxypyrrolidine derivative or it's enantiomer, which is a key intermediate for producing a high-quality optically active form of (3R,4S)-3-alkylaminomethyl-4-fluoropyrrolidine or it's enantiomer useful as an intermediate for producing pharmaceuticals.
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