Method of preparing biologically active formulations

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 9107804
APP PUB NO 20040185111A1
SERIAL NO

10728196

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Abstract

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The invention provides pellet for use as a core for a pharmaceutical dosage form having an inner and an outer zone where the inner zone includes a biologically active agent and said outer zone includes a layer formed by applying a substantially dry, free flowing inert powder which forms a non-tacky surface when placed in contact with water. The invention also provides a process for making pharmaceutical pellets where the core or at least one a layer on the core is formed by (a) contacting powder particles, adhering them to each other and compacting the adhered pellets by a rolling movement, wherein the degree of densification is controlled by the rolling movement; and (b) feeding a sufficient amount of a substantially dry, free flowing inert powder which forms a non-tacky surface when placed in contact with water to provide on said particles an outer zone including a layer formed from said substantially dry, free flowing inert powder.

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Patent Owner(s)

Patent OwnerAddress
NORTEC DEVELOPMENT ASSOCIATES INC100 SPEAR ROAD RAMSEY NJ 07446

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bretschneider, Frank Radeberg, DE 11 231
Fankhauser, Peter Ettingen, CH 53 392
Jones, David M Ramsey, US 76 897
Prasch, Armin Freiburg, DE 12 180
Rubino, Orapin P Towaco, US 6 82

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