Microfluidic apparatus and method for DNA extraction, amplification and analysis
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United States of America Patent
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Aug 11, 2015
Grant Date -
Oct 6, 2011
app pub date -
Oct 12, 2009
filing date -
Oct 10, 2008
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Abstract
An integrated gel based microfluidic sample processing device, suitable for forensic investigations at the scene of a crime, including a substrate having a plurality of micro-channels to form at least a DNA extraction chamber in fluidic cooperation with an amplification chamber which in turn is in fluidic cooperation with a separation and detection channel. The micro-channels containing a DNA extraction material and gel based reaction reagents necessary for processing the sample. The device further having electrical contacts for coupling to an external power source and capable of inducing electro-kinetic manipulation of the gel based reagents and DNA extracted from the sample throughout the device.
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