Electro spun nanofibrous wound dressing and a method of synthesizing the same
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United States of America Patent
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Aug 11, 2015
Grant Date -
Jun 13, 2013
app pub date -
Dec 7, 2011
filing date -
Dec 7, 2011
priority date (Note) -
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Abstract
The various embodiments herein provide an electro spun wound dressing comprising three nano fibrous layers and a method of synthesizing the same. The outer polymeric layer acts as a support layer for the other two layers and is hydrophilic in nature. The middle layer comprises a genipin cross linked reservoir layer loaded with a herbal extract of Melilotus officinalis and is hydrophobic or hydrophilic in nature. The second layer is cross-linked to control a release of the Melilotus officinalis extract in an aqueous environment. The third layer is a wound contacting inner layer comprising a non-cross-linked chitosan based nanofibrous layer that is hydrophilic in nature. Various additives are provided to enhance the mechanical or the chemical properties of the wound dressing and to control a release profile of the herbal extract.
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International Classification(s)
- A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....
- A61F:FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES....
- D06N:WALL, FLOOR, OR LIKE COVERING MATERIALS, e.g. LINO....
- A61L:METHODS OR APPARATUS FOR STERILISING MATERIALS OR ....
- B32B:LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA....
- D04H:MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAME....
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