O-(substituted benzyl) phosphoramidate compounds and therapeutic use
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United States of America Patent
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Aug 4, 2015
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app pub date -
Dec 30, 2011
filing date -
Jan 3, 2011
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Abstract
This application discloses novel phosphoramidate and phosphonoamidate prodrugs of nucleosides, nucleotides, C-nucleosides, C-nucleotides, phosphonates, and other alcohol-containing drugs; use of these prodrugs for treatment of infectious diseases and cancers, in particular, liver infections and cancers; and methods of preparing these novel phosphoramidate and phosphonoamidate prodrugs.
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