Combinations of MEK inhibitors and Raf kinase inhibitors and uses thereof
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United States of America Patent
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Aug 4, 2015
Grant Date -
May 31, 2012
app pub date -
Nov 30, 2010
filing date -
Jul 21, 2005
priority date (Note) -
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Abstract
This invention concerns combinations of inhibitors of MEK, Raf protein kinases, and other kinases including VEGFR1-3 and PDGFR-β. This invention also concerns pharmaceutical compositions comprising the compounds described herein and methods of use of the compounds and compositions described herein, including the use in the treatment and/or prevention of cancer and other hyperproliferative disorders.
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