Methods and compositions for increasing the efficiency of therapeutic antibodies using NK cell potentiating compounds

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United States of America Patent

PATENT NO 9090876
APP PUB NO 20110008335A1
SERIAL NO

12847090

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Abstract

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The present invention relates, generally, to methods and compositions for increasing the efficiency of therapeutic antibodies. Their efficiency is enhanced through the increase of the ADCC mechanism. More particularly, the invention relates to the use of a therapeutic antibody in combination with compounds that block an inhibitory receptor or stimulate an activating receptor of an NK cell in order to enhance the efficiency of the treatment with therapeutic antibodies in human subjects.

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Patent Owner(s)

Patent OwnerAddress
INNATE PHARMA S A13009 MARSEILLE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Romagne, Francois La Ciotat, FR 28 380
Velardi, Andrea Perugia, IT 4 138

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