Indolealkylamino-withasteroid conjugates and method of use
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United States of America Patent
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Jul 21, 2015
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May 9, 2013
app pub date -
Nov 5, 2012
filing date -
Nov 7, 2011
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Abstract
A group of indolealkylamino-withasteroid conjugates, isolated and purified from Withania somnifera, are described. A synthetic method of making an indolealkylamino-withasteroid compound is provided. In vitro acetyl cholinesterase inhibitory activity and methods for treatment of dementia and dementia-related disorders, such as Alzheimer's disease, and anxiety and depressive disorders in mammals are demonstrated with these novel compositions.
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