Methods for drug delivery comprising unfolding and folding proteins and peptide nanoparticles
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United States of America Patent
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Jun 30, 2015
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Aug 6, 2010
filing date -
Aug 11, 2009
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Abstract
The present invention provides preparation methods of protein nanoparticles for in vivo delivery of pharmacologically active agents, wherein said methods are to encase pharmaceutically active agents into proteins or peptides to form nanoparticles by unfolding the protein, and subsequently refolding or assembling the protein to produce a pharmacologically active agent encased within a protein nanoparticle.
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