Multi-stream high-pressure liquid chromatography module

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United States of America Patent

PATENT NO 9063158
APP PUB NO 20120193555A1
SERIAL NO

13499775

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Abstract

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An HPLC module utilizes a combination of compound-dedicated hardware providing line clearance between differing radiosynthesis and includes multiple compound-dedicated HPLC inject valves, each inject valve directing a fluid to a serially-connected HPLC column and UV flowcell so as to prevent cross-contamination between differing radiopharmaceutical syntheses. The module provides a disposable fluid path from each UV flowcell allowing for radioactive detection, fraction collection, formulation and final product dispensing. In this manner, a level of GMP compliance is achieved that is suitable for meeting the requirements of an MHRA approved site-license.

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Patent Owner(s)

Patent OwnerAddress
GE HEALTHCARE LIMITEDAMERSHAM PLACE LITTLE CHALFONT BUCKINGHAMSHIRE HP8 4SP

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Luthra, Sajinder London, GB 5 6
Shah, Farah Northwood, GB 3 17
Steel, Colin London, GB 7 58

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