2-((2S,3S,4R,5R)-5-((S)-3-amino-2-hydroxyprop-1-yl)-4-methoxy-3-(phenylsulfonylmethyl)tetrahydrofuran-2-yl)acetaldehyde derivatives and process for their preparation

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United States of America Patent

PATENT NO 9062020
APP PUB NO 20150011776A1
SERIAL NO

14369442

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Abstract

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Disclosed is a compound of formula 1, as shown below, where R1, R2, R3, R4, R5, R6 and R7 are as described herein. Also, disclosed is a process for the preparation of compounds of formula 1, and intermediates used therein. The compound of formula 1 can be useful for preparation of halichondrin analogs such as Eribulin.

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Patent Owner(s)

Patent OwnerAddress
ALPHORA RESEARCH INC2395 SPEAKMAN DRIVE SUITE 2001 MISSISSAUGA ONTARIO L5K 1B3

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Alberico, Dino Mississauga, CA 12 22
Gorin, Boris Oakville, CA 39 232
Pan, Ming Mississauga, CA 20 96
Rudolph, Alena Puslinch, CA 5 54
Souza, Fabio E S Mississauga, CA 37 36

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