Heparin binding epidermal growth factor (HB-EGF) for use in methods of treating and preventing intestinal injury related to hemorrhagic shock and resuscitation

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United States of America Patent

PATENT NO 9060977
APP PUB NO 20130165376A1
SERIAL NO

13346285

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Abstract

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The invention is related to methods of protecting, preventing and reducing intestinal injury in a human subject suffering from or at risk for shock, hemorrhagic shock or hemorrhagic shock and resuscitation (HS/R) comprising administering heparin binding epidermal growth factor (HB-EGF). The invention is also related to methods of inhibiting deterioration of intestinal blood flow and methods of preserving and increasing intestinal blood flow by administering HB-EGF to a human subject. In addition, the methods of the invention should improve the clinical outcome of human subject suffering from or at risk for shock, hemorrhagic shock or hemorrhagic shock and resuscitation.

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Patent Owner(s)

Patent OwnerAddress
NATIONWIDE CHILDREN'S HOSPITAL INC700 CHILDREN'S DRIVE COLUMBUS OH 43205

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Besner, Gail E Dublin, US 19 111
El-Assal, Osama N Gahanna, US 2 0

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11.5 Year Payment $7400.00 $3700.00 $1850.00 Dec 23, 2026