Glyco-engineered antibodies
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United States of America Patent
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Jun 9, 2015
Grant Date -
Nov 26, 2009
app pub date -
Jul 11, 2007
filing date -
Jul 11, 2006
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Abstract
The present invention relates to an antibody preparation comprising modified antibodies of an animal or derivatives or fragments thereof, specific for an antigen, characterized in that • the antibodies or derivatives or fragments thereof comprise an N-glycan structure free of fucose and xylose, and • at least 90%, preferably at least 95%, more preferred at least 99%, most preferred at least 100% of the modified antibodies, derivatives or fragments thereof lack a C-terminal lysine residue.
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