Solid-phase support for oligonucleotide synthesis and oligonucleotide synthesis method
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United States of America Patent
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Jun 2, 2015
Grant Date -
Nov 28, 2013
app pub date -
May 23, 2013
filing date -
May 23, 2012
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Abstract
The present invention provides a solid-phase support for oligonucleotide synthesis for synthesizing long chain oligonucleotide, RNA oligonucleotide and modified oligonucleotide at high synthetic quantity and high purity with a low loading amount of a linker. Provided is a solid-phase support for oligonucleotide synthesis comprising a porous resin bead having a monovinyl monomer unit, a crosslinkable vinyl monomer unit and a polyethylene glycol unit and a cleavable linker loaded on its surface,
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