Macromolecule transduction domains and methods for identification and uses thereof
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United States of America Patent
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May 26, 2015
Grant Date -
Jul 3, 2014
app pub date -
Nov 27, 2013
filing date -
Jan 29, 2007
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Abstract
The present invention discloses novel macromolecule transduction domain (MTD) peptides which facilitate the traverse of a biologically active molecule across the cell membrane. Also disclosed are polynucleotides encoding the MTD peptides, methods of identifying the MTD peptides; methods of genetically engineering a biologically active molecule to have cell permeability by using the MTD peptides, methods of importing a biologically active molecule into a cell by using the MTD peptides, and uses thereof.
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