Method for reducing interference and crosstalk in double optical tweezers using a single laser source, and apparatus using the same
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United States of America Patent
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May 19, 2015
Grant Date -
Jul 21, 2011
app pub date -
Jul 22, 2009
filing date -
Jul 22, 2008
priority date (Note) -
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Abstract
Experimental studies of single molecule mechanics require high force sensitivity and low drift, which can be achieved with optical tweezers through an optical tweezers apparatus for force measurements. A CW infrared laser beam is split by polarization and focused by a high numerical aperture objective to create two traps. The same laser is used to form both traps and to measure the force by back focal plane interferometry. Although the two beams entering the microscope are designed to exhibit orthogonal polarization, interference and a significant parasitic force signal occur. Comparing the experimental results with a ray optics model, the interference patterns are caused by the rotation of polarization on microscope lens surfaces and slides. Two methods for reducing the crosstalk are directed to polarization rectification by passing through the microscope twice and frequency shifting of one of the split laser beams.
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- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
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CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) | 75794 PARIS CEDEX 16 |
International Classification(s)

- 2009 Application Filing Year
- G21K Class
- 353 Applications Filed
- 196 Patents Issued To-Date
- 55.53 % Issued To-Date
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
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Bockelmann, Ulrich | Paris, FR | 9 | 27 |
# of filed Patents : 9 Total Citations : 27 | |||
Mangeol, Pierre | Abreschviller, FR | 1 | 1 |
# of filed Patents : 1 Total Citations : 1 |
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- 0 Citation Count
- G21K Class
- 0 % this patent is cited more than
- 10 Age
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11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Nov 19, 2026 |
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Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
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Legal Events
Date | Code | Event | Description |
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Dec 07, 2009 | STCH | INFORMATION ON STATUS: PATENT DISCONTINUATION | free format text: PATENT EXPIRED DUE TO NONPAYMENT OF MAINTENANCE FEES UNDER 37 CFR 1.362 |
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Nov 11, 2009 | FP | LAPSED DUE TO FAILURE TO PAY MAINTENANCE FEE | Effective Date: Nov 11, 2009 |
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Oct 14, 2008 | AS | ASSIGNMENT | free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:THE NORTH AMERICAN MANUFACTURING COMPANY, LTD.;REEL/FRAME:021849/0795 Owner name: FIVES NA CORP., OHIO Effective Date: Jul 31, 2008 free format text: CHANGE OF NAME;ASSIGNOR:FIVES NA CORP.;REEL/FRAME:021849/0887 Owner name: FIVES NORTH AMERICAN COMBUSTION, INC., OHIO Effective Date: Oct 14, 2008 |
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Nov 11, 1997 | I | Issuance | |
Jan 16, 1996 | F | Filing | |
Jan 16, 1996 | PD | Priority Date | |
Jan 15, 1996 | AS | ASSIGNMENT | free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:RAMSDELL, JOHN L.;HRABAK, STEVEN G.;REEL/FRAME:007836/0609 Owner name: NORTH AMERICAN MANUFACTURING COMPANY, OHIO Effective Date: Jan 15, 1996 |

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