Bombesin analog peptide antagonist conjugates

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United States of America Patent

PATENT NO 9035023
APP PUB NO 20110097266A1
SERIAL NO

12921209

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Abstract

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To provide a diagnostic and therapeutic medicament, a bombesin analog peptide antagonist conjugate is provided which has general Formula (I), wherein A is a metal chelator comprising at least one radionuclide metal, B is a spacer linked to N-terminal of C or a covalent bond and C is a bombesin analog peptide antagonist having a sequence as claimed, where further x is an integer from 1 to 3 and n is an integer from 1 to 6.

description='In-line Formulae' end='lead'[A-(B)n]x—C  (I)description='In-line Formulae' end='tail'

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Patent Owner(s)

Patent OwnerAddress
BAYER PHARMA AKTIENGESELLSCHAFT13353 BERLIN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Maecke, Helmut Lörrach, DE 2 13
Mansi, Rosalba Münchenstein, CH 3 14
Reubi, Jean Claude Wabern, CH 15 187

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