Anti-phospho-Akt antibodies

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United States of America Patent

PATENT NO 9029512
SERIAL NO

12618106

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Abstract

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The present invention relates to antibodies that immunospecifically bind to phospho-Akt and certain p-Akt substrates. The invention encompasses human and humanized forms of the antibodies and their use in treating cancers and other proliferative disorders. The invention also relates to p-Akt-derived peptides useful for preparing the antibodies. Methods and compositions for detecting, diagnosing, treating or ameliorating a disease or disorder, especially cancer and other proliferative disorders using the present antibodies also are disclosed.

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Patent Owner(s)

Patent OwnerAddress
NUCLEA BIOMARKERS LLC105 SOUTH STREET PITTSFIELD MA 01201

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Muraca, Patrick J Pittsfield, US 48 438

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