Microneedle device, and method for enhancing the efficacy of influenza vaccine by using microneedle device
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United States of America Patent
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May 12, 2015
Grant Date -
May 12, 2011
app pub date -
May 22, 2009
filing date -
Jun 30, 2008
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Abstract
The present invention provides a method for enhancing the immunogenicity using a microneedle device capable of enhancing the immunogenicity of an influenza vaccine. According to the method for enhancing the immunogenicity using the present microneedle device, a microneedle device having microneedles made of polylactic acid, coated with an influenza vaccine composed of an antigen having type A strain (H1N1), type A strain (H3N2), and type B strain as active ingredients is brought into direct contact with the skin so as to transcutaneously administer the aforementioned influenza vaccine. After the transcutaneous administration, lauryl alcohol is applied to the site of the skin where the microneedle device has been brought into direct contact.
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