Transgenic pig in which HO-1 and TNFR1-Fc are simultaneously expressed, and method for producing same
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United States of America Patent
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Apr 28, 2015
Grant Date -
Nov 1, 2012
app pub date -
Dec 21, 2010
filing date -
Dec 30, 2009
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Abstract
The present invention relates to a method for producing a transgenic pig in which immune rejection response is inhibited, and in which human HO-1 genes and TNFR1-Fe fusion genes are simultaneously expressed. The present invention also relates to a transgenic pig for organ transplantation, which is produced by the method, and in which immune rejection response is inhibited. The present invention also relates to a somatic-cell-donating cell strain for producing the transgenic pig, and to a method for producing organs, from the transgenic pig, in which the immune rejection response is inhibited.
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