5.9 kDa peptide immunoassay method
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United States of America Patent
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Apr 28, 2015
Grant Date -
Nov 1, 2012
app pub date -
Oct 13, 2010
filing date -
Oct 28, 2009
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Abstract
Disclosed is an immunoassay method whereby a 5.9 kDa peptide which results from the degradation of the α-E chain and α chain of human fibrinogens and which is used as a peptide marker for diagnosing hepatic disease can be specifically assayed in a biological sample containing contaminating peptides by bringing antibodies that recognize the N terminal of said peptide marker and antibodies that recognize the C terminal of said peptide marker into contact with said peptide marker, forming immune complexes of said peptide marker and the two antibodies, and immunoassaying the obtained immune complexes.
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