Method for producing 30-halogenated betulinic acid
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United States of America Patent
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Apr 21, 2015
Grant Date -
Oct 2, 2014
app pub date -
Mar 15, 2012
filing date -
Nov 18, 2011
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Abstract
The invention discloses a method for producing 30-halogenated betulinic acid. Betulin is used as a raw material and selectively oxidized and halogenated to generate 30-betulinic acid, and the selected oxidation and halogenation agent has high selectivity and does not affect C-3 hydroxyl or carbon-carbon double bonds. Oxidation and halogenation are completed in one step, so the process route is short, the treatment method is simple, and the product is purified easily.
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