Probe for detecting ABL gene mutation and uses thereof
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United States of America Patent
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Apr 21, 2015
Grant Date -
Jul 9, 2009
app pub date -
Feb 19, 2008
filing date -
Feb 20, 2007
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Abstract
Detection probes are provided that are capable of detecting a sequence to be detected containing a mutation even when a sequence not to be detected containing no mutation coexists with the sequence to be detected containing a mutation, which are different only in a single base from each other. At least one oligonucleotide selected from the group consisting of SEQ ID NOs: 2˜16 is used as a probe. Even in a sample containing an abl gene in which a mutation has occurred and an abl gene in which no mutation has occurred, the use of such probes in, for example, Tm analysis allows the mutation to be detected.
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