Extended-release oral dosage forms for poorly soluble amine drugs
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United States of America Patent
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Apr 21, 2015
Grant Date -
Apr 12, 2012
app pub date -
Oct 7, 2010
filing date -
Oct 7, 2010
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Abstract
Oral dosage forms for poorly soluble amine drugs are provided. Such dosage forms include an ionizable compound such as an organic acid, an amphiphilic polymer and a release rate-controlling membrane. Such dosage forms allow for the consistent release of the active agent in both gastric pH conditions and in the intestine. Methods of making such dosage forms are also provided.
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