Sterile hyaluronic acid polymer compositions and related methods
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United States of America Patent
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Apr 21, 2015
Grant Date -
Jan 15, 2009
app pub date -
Jun 30, 2008
filing date -
Jun 29, 2007
priority date (Note) -
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Abstract
The present application provides sterile hyaluronic polymer compositions than are useful, e.g., as medical devices, biomedical adhesives, and sealants. Generally, provided are sterile dry compositions comprising a thiol-derivatized hyaluronic acid and one or more stabilizing excipients. Also provided are related kits and methods. The compositions described herein are particularly robust to sterilizing irradiation, and substantially maintain both their molecular weight and gelation parameters such as gelation time after sterilization, such that such sterile compositions are capable of hydrogel formation.
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