Methods for microvesicle isolation and selective removal
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United States of America Patent
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Apr 14, 2015
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Dec 19, 2013
app pub date -
Jun 14, 2013
filing date -
Jun 14, 2012
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Abstract
The invention relates to compositions and methods for isolation of microvesicles produced by mammalian cells. These microvesicles, known as extracellular microvesicles or circulating microvesicles, are isolated from sample materials such as body fluids, or from cell culture media that has been used to culture and maintain mammalian cells in vitro. The isolation of microvesicles as described herein results in purification and concentration of the microvesicles.
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