Conjugated proteins and peptides
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United States of America Patent
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Apr 14, 2015
Grant Date -
Jan 19, 2012
app pub date -
Mar 4, 2010
filing date -
Mar 4, 2009
priority date (Note) -
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Abstract
Novel compounds of the general formula (I): in which X represents a polymer; Q represents a linking group; W represents an electron-withdrawing moiety or a moiety preparable by reduction of an electron-withdrawing moiety; each of R1 and R2 independently represents a hydrogen atom or a C1-4alkyl group; and either Z1 represents a protein or a peptide linked to CR2 via a nucleophilic moiety, and Z2 represents a molecule linked to CR2 via a nucleophilic moiety, or Z1 and Z2 together represent a single group derived from a protein or peptide linked to CR via two nucleophilic moieties.
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