Compositions and methods for the removal of biofilms

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United States of America Patent

PATENT NO 8999291
SERIAL NO

13073782

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Abstract

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This invention provides isolated or recombinant polypeptides that are useful to vaccinate individuals suffering from chronic/recurrent biofilm disease or as a therapeutic for those with an existing infection. The individual's immune system will then naturally generate antibodies which prevent or clear these bacteria from the host by interfering with the construction and or maintenance of a functional protective biofilm. Alternatively, antibodies to the polypeptides can be administered to treat or prevent infection. Bacteria that cannot form functional biofilms are more readily cleared by the remainder of the host's immune system.

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Patent Owner(s)

Patent OwnerAddress
RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL700 CHILDREN'S DRIVE COLUMBUS OH 43205

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bakaletz, Lauren O Columbus, US 72 970
Goodman, Steven D Hilliard, US 39 496

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