Methods for stem cell production and therapy

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 8993231
APP PUB NO 20100062435A1
SERIAL NO

12405944

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Abstract

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The present invention relates to methods for rapidly expanding a stem cell population with or without culture supplements in simulated microgravity conditions. The present invention relates to methods for rapidly increasing the life span of stem cell populations without culture supplements in simulated microgravity conditions. The present invention also relates to methods for increasing the sensitivity of cancer stem cells to chemotherapeutic agents by culturing the cancer stem cells under microgravity conditions and in the presence of omega-3 fatty acids. The methods of the present invention can also be used to proliferate cancer cells by culturing them in the presence of omega-3 fatty acids. The present invention also relates to methods for testing the sensitivity of cancer cells and cancer stem cells to chemotherapeutic agents by culturing the cancer cells and cancer stem cells under microgravity conditions. The methods of the present invention can also be used to produce tissue for use in transplantation by culturing stem cells or cancer stem cells under microgravity conditions. The methods of the present invention can also be used to produce cellular factors and growth factors by culturing stem cells or cancer stem cells under microgravity conditions. The methods of the present invention can also be used to produce cellular factors and growth factors to promote differentiation of cancer stem cells under microgravity conditions.

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Patent Owner(s)

Patent OwnerAddress
MARSHALL UNIVERSITY RESEARCH CORPORATION401 11TH STREET SUITE 1300 TECHNOLOGY TRANSFER OFFICE HUNTINGTON WV 25701

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Claudio, Pier Paolo Huntington, US 7 16
Valluri, Jagan V Huntington, US 2 5

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