Potentiation of autoimmune and inflammatory disease treatments by immune regulatory oligonucleotide (IRO) antagonists of TLR7 and TLR9

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United States of America Patent

PATENT NO 8987221
APP PUB NO 20110171209A1
SERIAL NO

12791636

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Abstract

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The invention provides the use of immune regulatory oligonucleotides (IRO) as antagonist of TLRs and potentiators of anti-inflammatory agents that inhibit TNF for the prevention and treatment of inflammatory and autoimmune diseases.

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Patent Owner(s)

Patent OwnerAddress
IDERA PHARMACEUTICALS INC167 SIDNEY STREET CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Agrawal, Sudhir Shrewsbury, US 223 8509
Kandimalla, Ekambar Southboro, US 59 812
Zhu, Fu-Gang Bedford, US 12 116

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