Methods and compositions for separating rare cells from fluid samples
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United States of America Patent
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Mar 24, 2015
Grant Date -
Aug 30, 2007
app pub date -
Aug 2, 2006
filing date -
Oct 11, 2001
priority date (Note) -
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Abstract
The present invention includes methods of enriching rare cells, such as cancer cells, from biological samples, such as blood samples. The methods include performing at least one debulking step on a blood sample and selectively removing at least one type undesirable component from the blood sample to obtain a blood sample that is enriched in a rare cell of interest. In some embodiments magnetic beads coupled to specific binding members are used to selectively removed components.
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