-associated infection and disease
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United States of America Patent
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Mar 24, 2015
Grant Date -
Aug 8, 2013
app pub date -
Apr 15, 2011
filing date -
Apr 15, 2010
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Abstract
Provided herein are reagents, compositions, and therapies with which to treat Clostridium difficile infection and related disease conditions and pathologies, such as Clostridium difficile-associated diarrhea, resulting from infection by Clostridium difficile bacteria and the enterotoxins produced by these bacteria. In particular, antibodies or antigen-binding fragments thereof that bind specifically to toxin A and/or toxin B of C difficile and neutralize the activities of these toxins; compositions comprising such antibodies; and methods of using the antibodies and the compositions are provided.
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