Onset-mitigating high-frequency nerve block

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United States of America Patent

PATENT NO 8983614
SERIAL NO

12739413

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Abstract

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A method of blocking signal transmission through a nerve with reduced onset activity includes applying an HFAC to an axon of a nerve to block the transmission of signals through the axon. The method may also include applying a direct current (DC) to the axon, increasing the amplitude of the DC over time to a predetermined amplitude, applying the HFAC, and then decreasing the DC. The method may also include temporarily reducing the amplitude of the HFAC to permit the transmission of signals through the axon and subsequently increasing the amplitude to block transmission without triggering an onset response. The method may also include temporarily applying an unbalanced charge to the nerve and then balancing the charge over time.

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Patent Owner(s)

Patent OwnerAddress
CASE WESTERN RESERVE UNIVERSITY2040 ADELBERT ROAD CLEVELAND OHIO 44106

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bhadra, Niloy Cleveland Heights, US 49 1163
Kilgore, Kevin L Cleveland Heights, US 46 1425

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