, nucleotide sequences to transform a microorganism to produce said peptides; methods to obtain the peptides; pharmaceutical compositions containing thereof and use thereof
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United States of America Patent
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Mar 17, 2015
Grant Date -
Sep 29, 2011
app pub date -
Mar 22, 2011
filing date -
Mar 23, 2010
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Abstract
The present invention is directed to an active agent with contraceptive properties which corresponds to a peptide fragment of the Latrodectus mirabilisi's venom. The peptide generally includes the amino acid sequence of SEQ ID NO 2 or sequences that are at least 85% similar, obtained by chemical synthesis or through recombinant DNA technologies. Furthermore, a pharmaceutical contraceptive composition comprising the peptide fragment and one or more pharmaceutically acceptable vehicles is also described. The peptide fragment and pharmaceutical compositions are useful as a contraceptive and spermicide agent.
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