Mutant glycerol dehydrogenase (GlyDH) for the production of a biochemical by fermentation
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United States of America Patent
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Mar 17, 2015
Grant Date -
May 31, 2012
app pub date -
Jul 30, 2010
filing date -
Jul 30, 2009
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Abstract
The present invention concerns a method for the production of 1,2-propanediol, comprising culturing a microorganism modified for an improved production of 1,2-propanediol in an appropriate culture medium and recovery of the 1,2-propanediol which may be further purified wherein the microorganism expresses a glycerol dehydrogenase (GlyDH) enzyme the inhibition of which activity by NAD+ and/or its substrate and/or its product is reduced.
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