Antibody targeting osteoclast-associated protein
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United States of America Patent
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Mar 17, 2015
Grant Date -
Apr 12, 2007
app pub date -
Aug 11, 2006
filing date -
Feb 12, 2004
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Abstract
The present invention relates to a method of detecting metabolic bone disorders using a gene expressed at a high level in osteoclasts, a method of screening for a compound effective for treatment and/or prevention of metabolic bone disorders, and a pharmaceutical composition for treatment and/or prevention of metabolic bone disorders. Specifically, the present invention relates to a method of detecting metabolic bone disorders using expression of the human DC-STAMP gene as an indicator, a pharmaceutical composition containing an antibody which is capable of specifically recognizing human DC-STAMP and suppressing formation of osteoclasts, and so forth.
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