Process for the asymmetric transfer hydrogenation of ketones
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United States of America Patent
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Mar 10, 2015
Grant Date -
May 16, 2013
app pub date -
Apr 14, 2011
filing date -
Apr 23, 2010
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Abstract
The invention relates to a process for the asymmetric transfer hydrogenation of a ketone substrate to produce as chiral secondary alcohol with an ee of greater than 85% in which an enantio-enriched chiral catalyst containing ruthenium or rhodium is used with a hydrogen donor and in which an anion exchange resin is used as a base.
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