Mutant YqhD enzyme for the production of a biochemical by fermentation
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United States of America Patent
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Mar 3, 2015
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May 17, 2012
app pub date -
Jul 30, 2010
filing date -
Jul 30, 2009
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Abstract
The present invention concerns a method for the production of a biochemical selected among acetol and 1,2-propanediol, 1,3-propanediol, ethylene glycol and 1,4-butanediol comprising culturing a microorganism modified for an improved production of the biochemical selected among acetol and 1,2-propanediol, 1,3-propanediol, ethylene glycol and 1,4-butanediol in an appropriate culture medium and recovery of the desired biochemical which may be further purified wherein the microorganism expresses a YqhD enzyme which catalytic efficiency toward NADPH is increased.
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