Method for improving cartilage repair and/or preventing cartilage degeneration in a joint
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United States of America Patent
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Feb 24, 2015
Grant Date -
May 16, 2013
app pub date -
Nov 14, 2012
filing date -
Feb 20, 2009
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Abstract
The invention is in the field of methods for medical treatment. It provides an improved method for repairing damaged cartilage and/or preventing cartilage degeneration in tissue, in particular in a joint by administering a pharmaceutically active agent directly into the fat pad of a joint. The pharmaceutically active agent is preferably selected from the group consisting of agents that stimulate chondrogenic differentiation and/or cartilage matrix synthesis; agents that inhibit osteogenesis and/or hypertrophy, anti-inflammatory agents, agents that inhibit apoptosis of chondrocytes, agents that inhibit senescence of chondrocytes and agents that enhance lubrication of a joint.
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