Modulation of estrogen receptor-related receptor gamma (ERRγ) and uses therefor
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United States of America Patent
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Feb 24, 2015
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Mar 1, 2012
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Mar 1, 2011
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This application provides methods of increasing vascularization, muscle performance, muscle rehabilitation, and/or mitochondrial activity in subjects in need thereof, by administering a therapeutically effective amount of one or more agents that increases ERRγ activity to the subject. Such agents can include one or more ERRγ agonists. In some examples the method does not require that the subject exercise, and as such, the subject may be sedentary (such as bedridden or in a wheelchair).
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