Fluorescent probe compounds, preparation method and application thereof

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United States of America Patent

PATENT NO 8962339
APP PUB NO 20120288947A1
SERIAL NO

13521047

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Abstract

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The present invention discloses a fluorescent probe compound which solved the problem of fluorescence quenching by Pd2+, and its preparation method and use as well. Excitation and emission wavelengths of the probe compound are in visible light region. The probe compound is highly sensitive and displays good selectivity for Pd2+ in near-neutral pH range. In detection of Pd2+ in 0-10 ppb level, fluorescence is evidently enhanced, and Pd2+ in the level as low as 5 nM can be detected. Fluorescence intensity is well linearly correlated to Pd2+ concentration. The probe compound can be used for detection of contaminating palladium and residual palladium in drug, soil, water sample and reactor.

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Patent Owner(s)

Patent OwnerAddress
DALIAN UNIVERSITY OF TECHNOLOGYNO 2 LINGGONG ROAD LIAONING DALIAN 116024
DALIAN CHROMAS BIOSCIENCE CO LTDNO 43 HUOJU ROAD DALIAN LIAONING 116024

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fan, Jiangli Dalian, CN 16 23
Li, Honglin Dalian, CN 17 320
Peng, Xiaojun Dalian, CN 22 52
Sun, Shiguo Dalian, CN 10 88
Wang, Jingyun Dalian, CN 10 6

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