Isatin derivatives for use as in vivo imaging agents
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United States of America Patent
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Feb 24, 2015
Grant Date -
Aug 11, 2011
app pub date -
Sep 4, 2009
filing date -
Sep 5, 2008
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Abstract
Isatin 5-sulfonamide derivatives, pharmaceutical compositions comprising the derivatives, their use as molecular imaging agents, their use for the diagnosis or treatment of diseases or disorders associated with dysregulation of apoptosis, methods for synthesizing the derivatives, methods for the molecular imaging of caspase activity and apoptosis, and methods of assessing the therapeutic effect of a test substance on caspase activity are disclosed.
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