Inhibition of gliadin peptides

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United States of America Patent

PATENT NO 8957032
APP PUB NO 20110275562A1
SERIAL NO

12991658

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Abstract

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Novel compounds and methods for the inhibition of biological barrier permeability and for the inhibition of peptide translocation across biological barriers are identified. Assays for determining modulators of biological barrier permeability and for peptide translocation across biological barriers are provided. Methods for treating diseases relating to aberrant biological barrier permeability and peptide translocation across biological barriers are provided. Such diseases include celiac disease, necrotizing enterocolitis, diabetes, cancer, inflammatory bowel diseases, asthma, COPD, excessive or undesirable immune response, gluten sensitivity, gluten allergy, food allergy, rheumatoid arthritis, multiple sclerosis, immune-mediated or type 1 diabetes mellitus, systemic lupus erythematosus, psoriasis, scleroderma and autoimmune thyroid diseases.

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Patent Owner(s)

Patent OwnerAddress
INTERLUDE BIOPHARMA CO1450 BRICKELL AVE MIAMI FL 33131

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Alkan, Sefik Baltimore, US 16 226
Carrasco, Rosa A Baltimore, US 6 33
Durai, Malarvizhi Ellicott City, US 8 33
Kitchens, Kelly Marie Laurel, US 6 33
Poloso, Neil Rockville, US 7 33
Tamiz, Amir Silver Spring, US 19 70

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