Method of making composite particles for use in pharmaceutical compositions and composite particles and compositions thereof
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United States of America Patent
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Feb 17, 2015
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app pub date -
Sep 20, 2012
filing date -
Nov 30, 2000
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Abstract
The invention relates to a method for making composite active particles for use in a pharmaceutical composition for pulmonary administration, the method comprising a milling step in which particles of active material are milled in the presence of particles of an additive material which is suitable for the promotion of the dispersal of the composite active particles upon actuation of an inhaler. The invention also relates to compositions for inhalation prepared by the method.
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