Granule and preparation method thereof
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United States of America Patent
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Feb 10, 2015
Grant Date -
Jan 14, 2010
app pub date -
Jun 22, 2007
filing date -
Jun 23, 2006
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Abstract
A pharmaceutical granule whose shape is spherical or sphere-like shape with a bulk density of 0.6-1.3 g/ml and a dissolution time of 0.5-5 minutes, which is prepared as follows: mother granules are filled into a fluidized-bed as bed charge; active pharmaceutical ingredients are prepared into a suspension or solution whose viscosity is adjusted to 6.0-9.8 Mpa·S with viscosity adjusting agent; then it is sprayed onto surface of said mother granule to obtain final granule.
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