Phosphonated glycopeptide and lipoglycopeptide antibiotics and uses thereof for the prevention and treatment of bone and joint infections

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United States of America Patent

PATENT NO 8946144
APP PUB NO 20100113333A1
SERIAL NO

12520364

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Abstract

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The present invention is directed to antimicrobial compounds which have an affinity for binding bones. More particularly, the invention is directed to phosphonated derivatives of glycopeptide or lipoglycopeptide antibiotics. These compounds are useful as antibiotics for the prevention or treatment of bone and joint infections, especially for the prevention and treatment of osteomyelitis.

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Patent Owner(s)

Patent OwnerAddress
THE MEDICINES COMPANY9 SYLVAN WAY PARSIPPANY NJ 07054

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ciblat, Stephane Montréal, CA 57 252
Dietrich, Evelyne Laval, CA 20 32
Rafai, Far Adel Ville Mont-Royal, CA 13 27
Tanaka, Kelly Toronto, CA 4 12

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