Methods of treatment with compositions that include hemagglutinin
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United States of America Patent
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Feb 3, 2015
Grant Date -
May 30, 2013
app pub date -
Feb 6, 2013
filing date -
Mar 7, 2006
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Abstract
Methods that stimulate a protective immune response in a subject include a portion of a protein from a naturally occurring viral hemagglutinin, wherein the protein portion includes at least a portion of a globular head and at least a portion of at least one secondary structure that causes the globular head to essentially retain its tertiary structure, and wherein the protein portion lacks a transmembrane domain, a cytoplasmic domain and an HA2 subunit. Compositions administered to the subject can further include a carrier and can be administered in single or multiple doses.
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